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| Titre : | Pharmacokinetics of Mirtazapine and Its Main Metabolites after Single Oral Administration in Fasting/Fed Horses (2013) |
| Auteurs : | M. Giorgi ; M. Sgorbini ; B. Sheikholeslami ; M.R. Rouini ; H. Lavasani ; V. Nikoui ; A. Bakhtiarian |
| Type de document : | Article : texte imprimé |
| Dans : | JOURNAL OF EQUINE VETERINARY SCIENCE (Vol. 33, n6, 2013-06-01) |
| Article en page(s) : | p 410-414 |
| Langues: | Anglais |
| Mots-clés : |
Mots-clés cheval EXPERIMENTATION ; METABOLITE ; PRODUIT PHARMACEUTIQUEEquivoc Jument ; Recherche |
| Résumé : | Mirtazapine (MRZ) is a human antidepressant drug that is metabolized, predominantly by the cytochrome P450 enzyme system, to 8-OH mirtazapine (8-OH MRZ) and dimetilmirtazapine (DMR) metabolites. In veterinary medicine, this drug is currently administered to cats and dogs with anorexia, although it could also have applications as an antidepressant, antiemetic, and analgesic agent in these species. The aim of this study was to assess the pharmacokinetics of MRZ and its metabolites DMR and 8-OH MRZ in horses |
| Cote du document numérique : | 16025 |
| Classement cheval : | F20 |
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| Code-barres | Cote | Support | Localisation | Section | Disponibilité |
|---|---|---|---|---|---|
| 107397 | JEVS | Revue | Haras national du Pin | Archives | Exclu du prêt |